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KMID : 0383820080640050341
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Tuberculosis and Respiratory Diseases
2008 Volume.64 No. 5 p.341 ~ p.346
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The Clinical Characteristics and Outcomes of Short-term Treatment
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You Seung-Soo
Kwon Ji-Suk
Kang Yeh-Rim
Lee Jeong-Woo
Cha Seung-Ick
Park Jae-Yong
Jung Tae-Hoon
Kim Chang-Ho
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Abstract
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Background: Recurrent pulmonary tuberculosis (TB) can be due to relapse of the original infecting strain or due
to reinfection with a new strain of Mycobacterium tuberculosis. We investigated the clinical characteristics and efficacy of short-term treatment (6 months) in patients with recurrent pulmonary TB.
Methods: Twenty-nine patients with recurrent pulmonary TB were compared with control patients who received
primary treatment for pulmonary TB with respect to drug sensitivity and outcomes of treatment.
Results: Most patients with recurrent pulmonary TB (25 cases, 86.2%) recurred more than 2 years after the
completion of previous treatment. Twenty-three patients (82.1%) with recurrent pulmonary TB were sensitive to all anti-tuberculous drugs and a ratio was similar to the drug sensitivities observed in control patients. The outcomes of short-term treatment in patients with drug-sensitive TB were not significantly different between the two groups.
Conclusion: Recurrent pulmonary TB in the study area was likely due to reinfection with new strains. Thus the
short-term treatment of patients with drug-sensitive recurrent pulmonary TB may be successful. (Tuberc Respir Dis 2008;64:341-346)
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KEYWORD
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Recurrent pulmonary tuberculosis, Reinfection, Relapse
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